Possible Anticancer Mechanisms of Some Costus speciosus Active Ingredients Concerning Drug Discovery
نویسندگان
چکیده
منابع مشابه
Possible Anticancer Mechanisms of Some Costus speciosus Active Ingredients Concerning Drug Discovery
Costus speciosus is native to South East Asia, especially found in India, Srilanka, Indonesia and Malaysia. C. speciosus have numerous therapeutic potentials against a wide variety of complains. The therapeutic properties of C. speciosus are attributed to the presence of various ingredients such as alkaloids, flavonoids, glycosides, phenols, saponins, sterols and sesquiterpenes. This review pre...
متن کاملCostus speciosus (Keukand): A review
Costus speciosus Koen. (Keu, Crape ginger), an Indian ornamental plant, has long been medicinally used in traditional systems of medicine. The plant has been found to possess diverse number of pharmacological activities. The present article gives an account of updated information on its phytochemical and pharmacological properties. The review reveals that wide numbers of phytochemical constitue...
متن کاملAnticancer and apoptotic effects on cell proliferation of diosgenin isolated from Costus speciosus (Koen.) Sm
BACKGROUND Diosgenin, a naturally occurring steroid saponin found abundantly in C. speciosus, is a well-known precursor of various synthetic steroidal drugs that are extensively used in the pharmaceutical industry. METHODS The present study was conducted to evaluate the in vitro anticancer and apoptotic effects on cell proliferation of diosgenin isolated from C. speciosus (Koen.) Sm. RESULT...
متن کاملCostus speciosus: An Important Medicinal Plant
Costus speciosus is an important medicinal and ornamental plant used to cure different diseases. The plant has been found to possess many pharmacological activities such as antibacterial, antifungal, anticholineesterase, antioxidant, antihyperglycemic, antiinflammatory, analgesic, antipyretic, antidiuretic, larvicidal, antistress and estrogenic activity. The rhizomes of Costus speciosus are bit...
متن کاملMolecular mechanisms of anti-hyperglycemic effects of Costus speciosus extract in streptozotocin-induced diabetic rats
OBJECTIVES To investigate the mechanisms of the anti-hyperglycemic effect of Costus speciosus (C. speciosus) root ethanolic extracts (CSREt) by assessing its action on insulin synthesis and glucose catabolic enzyme gene expression and activities in streptozotocin (STZ) diabetic rats. METHODS This study was carried out at the Biochemical Laboratory, Faculty of Veterinary Medicine, Zagazig Univ...
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ژورنال
عنوان ژورنال: Current Drug Discovery Technologies
سال: 2016
ISSN: 1570-1638
DOI: 10.2174/1570163813666160802154403